This book offers a comprehensive overview of current challenges and strategies to regenerate load-bearing and calcified human tissues, including bone, cartilage,tendon, ligaments and dental structures (dentin, enamel, cementum and periodontal ligament). Tissue engineering has long held great promises as an improved treatment option for conditions affecting mineralized and load-bearing structures in the body. Although significant progress has been achieved in recent years, a number of challenges still exist.Scaffold vascularization, new biofabrication methods (3D printing, lithography, microfabrication), peptide conjugation methods, interface engineering, scaffold mechanical properties, iPS cells, organs-on-a-chip, are some of the topics discussed in this book. More specially, in the first section readers will find an overview of emerging biofabrication methods. In section 2, applied strategies for regeneration of (2.1) bone, cartilage and ligament, as well as (2.2) dentin, cementum, enamel and periodontal ligament are discussed across 14 chapters.While other volumes have addressed the regeneration of individual tissues, or exclusively focused on different regenerative strategies, the focus of this work is to bring together researchers integrating backgrounds in materials sciences, engineering, biology, mechanics, fluidics, etc, to address specific challenges common to regeneration of several load-bearing and calcified tissues. Therefore, this book provides a unique platform to stimulate progress in the regeneration of functional tissue substitutes.We envision that this book will represent a valuable reference source for university and college faculties, post-doctoral research fellows, senior graduate students, and researchers from R&D laboratories in their endeavors to fabricate biomimetic load bearing tissues.
This book offers a timely and comprehensive snapshot of research and developments in the field of control engineering. Covering a wide range of theoretical and practical issues, the contributions describes a number of different control approaches, such adaptive control, fuzzy and neuro-fuzzy control, remote and robust control systems, real time an fault tolerant control, among others. Sensors and actuators, measurement systems, renewable energy systems, aerospace systems as well as industrial control and automation, are also comprehensively covered. Based on the proceedings of the 14th APCA International Conference on Automatic Control and Soft Computing, held on July 1-3, 2020, in Bragança, Portugal, the book offers a timely and thoroughly survey of the latest research in the field of control, and a source of inspiration for researchers and professionals worldwide.